Discovery of farnesoid X receptor and its role in bile acid metabolism
John Y.L. Chiang, Jessica M. Ferrell
Topics & Concepts
Farnesoid X receptorBile acidCholesterol 7 alpha-hydroxylaseG protein-coupled bile acid receptorCYP8B1Enterohepatic circulationInternal medicineBiologyEndocrinologyNuclear receptorSmall heterodimer partnerBiochemistryMedicineGeneTranscription factorDrug Transport and Resistance MechanismsLiver Disease Diagnosis and TreatmentPediatric Hepatobiliary Diseases and Treatments