Serum miR-497-5p serves as a diagnostic biomarker for acute coronary syndrome and predicts the occurrence of major adverse cardiovascular events after percutaneous coronary intervention
Tao Chen, Xueshan Zhang, Wei Qian, Ran Zhou, Mingyu Su, Yanfeng Ma
Abstract
= 0.019). Finally, miR-497-5p positively correlated with endothelial proinflammatory and adhesion factors. Our study suggests that serum miR-497-5p is a potential diagnostic marker for ACS and its elevated levels can predict a high risk of MACEs in ACS patients after PCI. And this may be associated with vascular endothelial injury.
Topics & Concepts
MedicineAcute coronary syndromePercutaneous coronary interventionInternal medicineCardiologyBiomarkerMyocardial infarctionChemistryBiochemistryAtherosclerosis and Cardiovascular DiseasesCardiovascular Disease and AdiposityCoronary Interventions and Diagnostics