IGFBP2 regulates PD-L1 expression by activating the EGFR-STAT3 signaling pathway in malignant melanoma
Ting Li, Chao Zhang, Gang Zhao, Xinwei Zhang, Mengze Hao, Shafat Hassan, Min Zhang, Hong Zheng, Da Yang, Liang Liu, Farideh Mehraein‐Ghomi, Xu Bai, Kexin Chen, Wei Zhang, Jilong Yang
Topics & Concepts
MelanomaPD-L1ImmunotherapyCancer researchSignal transductionDownregulation and upregulationImmune systemImmune checkpointBlockadeMedicineRegulatorIn vivoBiologyImmunologyReceptorInternal medicineCell biologyBiotechnologyBiochemistryGeneCancer Immunotherapy and BiomarkersCytokine Signaling Pathways and InteractionsCancer Cells and Metastasis