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A WISP1 antibody inhibits MRTF signaling to prevent the progression of established liver fibrosis

Ying Xi, Ryan LaCanna, Hsiao‐Yen Ma, Elsa-Noah N’Diaye, Sarah Gierke, Patrick Caplazi, Meredith Sagolla, Zhiyu Huang, Laura Lucio, Alexander Arlantico, Surinder Jeet, Hans D. Brightbill, Claire Emson, Aaron K. Wong, Katrina B. Morshead, Daryle J. DePianto, Merone Roose‐Girma, Charles Yu, Lucinda Tam, Guiquan Jia, Thirumalai R. Ramalingam, Scot A. Marsters, Avi Ashkenazi, Si‐Hyun Kim, Ryan Kelly, Shuang Wu, Paul J. Wolters, Ariel E. Feldstein, Jason A. Vander Heiden, Ning Ding

2022Cell Metabolism50 citationsDOI

Topics & Concepts

MyofibroblastFibrosisCancer researchMedicineSteatohepatitisTumor progressionSignal transductionImmunologyBiologyFatty liverPathologyCancerInternal medicineDiseaseCell biologyConnective Tissue Growth Factor ResearchLiver physiology and pathologyLiver Disease Diagnosis and Treatment
A WISP1 antibody inhibits MRTF signaling to prevent the progression of established liver fibrosis | Litcius