Fenamates and ibuprofen as foundational components in the synthesis of innovative, targeted COX-2 anti-inflammatory drugs, undergoing thorough biopharmacological assessments and in-silico computational studies
Mohamed K. Elgohary, Mahmoud S. Elkotamy, Mahmoud Abdelrahman Alkabbani, Hatem A. Abdel‐Aziz
Topics & Concepts
IbuprofenChemistryMefenamic acidPharmacologyIn vivoIn silicoCyclooxygenaseIn vitroCarrageenanPotencyPharmacophoreAnti-inflammatoryFlurbiprofenArachidonic acidAnalgesicBiochemistryEnzymeMedicineGeneBiotechnologyBiologyInflammatory mediators and NSAID effectsSynthesis and biological activityComputational Drug Discovery Methods