Development and validation of a nonenhanced CT based radiomics model to detect brown adipose tissue
Junhao Li, Rui Zuo, U. Joseph Schoepf, Joseph P. Griffith, Shiyao Wu, Changsheng Zhou, Xingzhi Chen, Weixiong Tan, Zhen Zhou, Hong Gao, Longjiang Zhang, Guifen Yang
Abstract
We developed and validated a nonenhanced CT based reliable radiomics model for detecting BAT with PET-CT findings as reference standard. Radiomics signatures from nonenhanced CT can reliably detect BAT and have promising potential to be used in routine clinical settings. Importantly, our study showed that patients with BAT had less cardiovascular calcification.
Topics & Concepts
RadiomicsLasso (programming language)MedicineCohortNuclear medicinePositron emission tomographyCorrelationRadiologyComputer sciencePathologyMathematicsGeometryWorld Wide WebAdipose Tissue and MetabolismCardiovascular Disease and AdiposityAdipokines, Inflammation, and Metabolic Diseases