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Novel pathways of fluoride-induced hepatotoxicity: P53-dependent ferroptosis induced by the SIRT1/FOXOs pathway and Nrf2/HO-1 pathway

Dongxu Wang, Kai Yin, Yue Zhang, Hongmin Lu, Lulu Hou, Hongjing Zhao, Mingwei Xing

2022Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology51 citationsDOI

Topics & Concepts

Lipid peroxidationFluorideLiver injuryLiver damageOxidative stressChemistryPharmacologyMedicineCancer researchInternal medicineBiochemistryInorganic chemistryFerroptosis and cancer prognosisCircular RNAs in diseasesCancer, Lipids, and Metabolism
Novel pathways of fluoride-induced hepatotoxicity: P53-dependent ferroptosis induced by the SIRT1/FOXOs pathway and Nrf2/HO-1 pathway | Litcius