Redox-active benzimidazolium sulfonamides as cationic thiolating reagents for reductive cross-coupling of organic halides
Weigang Zhang, Mengjun Huang, Zhenlei Zou, Zheng‐Guang Wu, Shengyang Ni, Lingyu Kong, You‐Xuan Zheng, Yi Wang, Yi Pan
Abstract
R reagent provides a bench-stable cationic precursor to generate a portfolio of highly active N-S intermediates, which can be successfully applied in cross-electrophilic coupling with various organic halides. The employment of an electrophilic sulfur source solved the problem of catalyst deactivation and avoided odorous thiols, featuring practical conditions, broad substrate scope, and excellent tolerance.
Topics & Concepts
ReagentChemistryHalideCationic polymerizationRedoxCombinatorial chemistryCoupling reactionOrganic chemistryCatalysisSulfur-Based Synthesis TechniquesChemical Synthesis and ReactionsRadical Photochemical Reactions