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Propagation of pathologic α-synuclein from kidney to brain may contribute to Parkinson’s disease

Xin Yuan, Shuke Nie, Yingxu Yang, Congcong Liu, Danhao Xia, Lanxia Meng, Xia Yue, Hua Su, Chun Zhang, Lihong Bu, Min Deng, Keqiang Ye, Jing Xiong, Liam Chen, Zhentao Zhang

2025Nature Neuroscience61 citationsDOI

Topics & Concepts

NeuroscienceParkinson's diseaseAlpha-synucleinDiseaseMedicineNeuroscientistPsychologyPathologyCentral nervous systemOligodendrocyteMyelinParkinson's Disease Mechanisms and TreatmentsNeurological disorders and treatmentsNeurological and metabolic disorders
Propagation of pathologic α-synuclein from kidney to brain may contribute to Parkinson’s disease | Litcius