Catalyst-Controlled Direct Oxysulfonylation of Alkenes by Using Sulfonylazides as the Sulfonyl Radical
Rongxiang Chen, Yaoxue Tang, Xiaohui He, Kai‐Kai Wang, Lina Ding, Lantao Liu
Abstract
A copper/cobalt-catalyzed difunctionalization of alkenes with sulfonylazides and tert -butyl hydroperoxide has been achieved. This protocol provides an efficient and direct oxysulfonylation approach to β-ketosulfones and β-sulfonyl peroxides in moderate to good yields under mild conditions. This methodology applies sulfonylazides as a new sulfonyl radical source and features a wide substrate scope and good functional group tolerance.
Topics & Concepts
SulfonylChemistryCatalysisFunctional groupSubstrate (aquarium)Combinatorial chemistryCobaltOrganic chemistryGeologyAlkylPolymerOceanographySulfur-Based Synthesis TechniquesChemical Synthesis and ReactionsCatalytic C–H Functionalization Methods