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Discovery of N-(1,3,4-thiadiazol-2-yl)benzamide derivatives containing a 6,7-methoxyquinoline structure as novel EGFR/HER-2 dual-target inhibitors against cancer growth and angiogenesis

Xinyang Li, De-pu Wang, Shuai Li, Wen-han Xue, Xin-hua Qian, Kai-li Liu, Yuheng Li, Qi-qi Lin, Gang Dong, Fan‐hao Meng, Lingyan Jian

2021Bioorganic Chemistry23 citationsDOI

Topics & Concepts

ChemistryAngiogenesisBenzamideCancer researchCancer cellCell growthIn vivoCancerPharmacologyBiochemistryStereochemistryBiologyInternal medicineMedicineBiotechnologyHER2/EGFR in Cancer ResearchSynthesis and biological activityQuinazolinone synthesis and applications
Discovery of N-(1,3,4-thiadiazol-2-yl)benzamide derivatives containing a 6,7-methoxyquinoline structure as novel EGFR/HER-2 dual-target inhibitors against cancer growth and angiogenesis | Litcius