Maturation of iPSC-derived cardiomyocytes in a heart-on-a-chip device enables modeling of dilated cardiomyopathy caused by R222Q-SCN5A mutation
Marianne Wauchop, Naimeh Rafatian, Yimu Zhao, Wenliang Chen, Mark Gagliardi, Stéphane Massé, Brian Cox, Patrick F.H. Lai, Timothy Liang, Shira Landau, Stephanie Protze, Xiao Gao, Erika Yan Wang, Kelvin Chan Tung, Zachary Laksman, Rick Xing Ze Lu, Gordon Keller, Kumaraswamy Nanthakumar, Milica Radisic, Peter H. Backx
Topics & Concepts
Dilated cardiomyopathyMaterials scienceCardiomyopathyCardiologyInternal medicineHeart failureMutationChipMedicineGeneticsBiologyGeneElectrical engineeringEngineeringCardiomyopathy and Myosin StudiesCardiac electrophysiology and arrhythmiasNeuroscience and Neural Engineering