High glucose-stimulated enhancer of zeste homolog-2 (EZH2) forces suppression of deptor to cause glomerular mesangial cell pathology
Falguni Das, Amit Bera, Nandini Ghosh‐Choudhury, Kavitha Sataranatarajan, Amrita Kamat, Balakuntalam S. Kasinath, Goutam Ghosh Choudhury
Topics & Concepts
mTORC1mTORC2PI3K/AKT/mTOR pathwayCancer researchEZH2Downregulation and upregulationCell biologyEndocrinologyChemistryBiologyInternal medicineHistoneMedicineSignal transductionBiochemistryGeneRenal Diseases and GlomerulopathiesPI3K/AKT/mTOR signaling in cancerEpigenetics and DNA Methylation