Zebrafish harbor diverse intestinal macrophage populations including a subset intimately associated with enteric neural processes
Christina Graves, Angela Chen, Victoria Kwon, Celia E. Shiau
Abstract
zebrafish, we found a depletion of muscularis but not mucosal macrophages, and that they may be dispensable for gross intestinal transit in adults but not during development. These characterizations provide first insights into intestinal macrophages and their association with the enteric nervous system from development to adulthood in teleosts.
Topics & Concepts
ZebrafishEnteric nervous systemBiologyMacrophageCell biologyGut–brain axisIntestinal mucosaNeuroscienceImmunologyPathologyGut floraGeneticsInternal medicineMedicineGeneIn vitroZebrafish Biomedical Research ApplicationsNeuroinflammation and Neurodegeneration MechanismsNeonatal and fetal brain pathology