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Integrated single-cell chromatin and transcriptomic analyses of human scalp identify gene-regulatory programs and critical cell types for hair and skin diseases

Benjamin Ober‐Reynolds, Chen Wang, Justin Ko, Eon J. Rios, Sumaira Z. Aasi, Mark M. Davis, Anthony E. Oro, William J. Greenleaf

2023Nature Genetics71 citationsDOIOpen Access PDF

Topics & Concepts

BiologyEnhancerHair follicleGeneticsTranscriptomeGeneSingle-nucleotide polymorphismChromatinCell typeTranscription factorGene regulatory networkComputational biologyRegulation of gene expressionGene expressionGenome-wide association studyCellCell biologyGenotypeHair Growth and Disordersmelanin and skin pigmentationSkin and Cellular Biology Research
Integrated single-cell chromatin and transcriptomic analyses of human scalp identify gene-regulatory programs and critical cell types for hair and skin diseases | Litcius