Metal-free efficient synthesis of aryl sulfonamides from <i>N</i> -hydroxy sulfonamide and amines
E. V. Venkat Shivaji Ramarao, Jayshree Solanke, Rana Chatterjee, Savita Gat, V. Dhayalan, Rambabu Dandela
Abstract
the oxidative cleavage of an S-N bond. A variety of aryl sulfonamides were prepared in moderate to good yields using readily available starting materials and the biomass-derived 2-MeTHF solvent. The present method has the advantages of using metal-free reagents, an eco-friendly medium, cost-effective reagents, wide substrate scope, and mild conditions.
Topics & Concepts
SulfonamideArylChemistryMetalCombinatorial chemistryOrganic chemistryAlkylSulfur-Based Synthesis TechniquesChemical synthesis and alkaloidsCatalytic C–H Functionalization Methods