A pan-coronavirus peptide inhibitor prevents SARS-CoV-2 infection in mice by intranasal delivery
Lili Wu, Anqi Zheng, Yangming Tang, Yan Chai, Jiantao Chen, Lin Cheng, Yu Hu, Jing Qu, Wenwen Lei, William Jun Liu, Guizhen Wu, Shaogui Zeng, Hang Yang, Qihui Wang, George F. Gao
Topics & Concepts
Nasal administrationSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)VirologyCoronavirusCoronavirus disease 2019 (COVID-19)PeptideSevere acute respiratory syndrome coronavirusHeptad repeatVero cell2019-20 coronavirus outbreakMedicineBiologyVirusPeptide sequenceGeneGeneticsPathologyInfectious disease (medical specialty)BiochemistryOutbreakDiseaseSARS-CoV-2 and COVID-19 ResearchInfluenza Virus Research Studiesinterferon and immune responses