Evaluation of copper nanoparticles and copper sulfate effect on immune status, behavior, and productive performance of broilers
Sara E. El-Kazaz, Mona Hafez
Abstract
OBJECTIVE: ) effect on immunity, pro-inflammatory cytokine, oxidant/antioxidant balance, different behavioral patterns, growth rate, and weight gain by adding them in drinking water of broilers. MATERIALS AND METHODS: = 25) for 5 weeks of age. Blood samples collected for estimating immunoglobulins (A, G, and M), superoxide dismutase, pro-inflammatory (IL-6), erythrocyte sedimentation rate, heterophil/lymphocyte (H/L) ratio, malondialdehyde (MDA), corticosterone hormone, and lymphoid organs index weight. Moreover, behavioral observations were undertaken from the 2nd week until the 5th week of age for measuring different behavioral patterns (feeding, drinking, crouching, body care, and comfort behaviors). Chicks were individually weighed weekly (gm); also, the weight gain, the intake of food, and the ratio of feed conversion were calculated. RESULTS: treated groups. Conversely, erythrocyte sedimentation rate, H/L ratio, MDA, and corticosterone hormone were reduced by Cu-NP treatment. Moreover, Cu-NP has a positive effect on all behavioral patterns more than other groups which significantly reflect on the weight of the body, gaining of weight, and the intake of food in the Cu-NP treated group of birds. CONCLUSION: .