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Synthesis of a Series of 12-Membered Azobenzene Macrocycles and Tuning of the Half-Life of the Thermal <i>Z</i>–<i>E</i> Isomerization

Souvik Ghosh, Christoph Eschen, Nadi Eleya, Anne Staubitz

2022The Journal of Organic Chemistry15 citationsDOI

Abstract

Azobenzene macrocycles (AzMs) represent a class of azobenzene that are typically photoswitchable with good switching yields of E and Z isomers at certain photostationary states. Here, the synthesis and versatile functionalization of 12-membered AzMs is presented to obtain various meta- and para-aryl-substituted AzMs in high yields of 71–98%. At different positions in the periphery, these substituents significantly impact on the thermal half-lives of the less-stable Z isomers. Para-substitution leads to faster thermal relaxation than meta-substitution, and electron-donating groups lead to a faster relaxation than electron-withdrawing groups.

Topics & Concepts

AzobenzeneIsomerizationArylRelaxation (psychology)Azo compoundChemistryPolar effectMaterials sciencePhotochemistryMoleculeOrganic chemistryPolymerCatalysisAlkylPsychologySocial psychologyPhotochromic and Fluorescence ChemistryPhotoreceptor and optogenetics researchSynthesis and Properties of Aromatic Compounds
Synthesis of a Series of 12-Membered Azobenzene Macrocycles and Tuning of the Half-Life of the Thermal <i>Z</i>–<i>E</i> Isomerization | Litcius