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COVID-19 Outbreak and Emerging Management through Pharmaceutical Therapeutic Strategy

Md. Habibur Rahman, Rokeya Akter, Tapan Behl, Md. Arifur Rahman Chowdhury, Manirujjaman Manirujjaman, Israt Jahan Bulbul, Shimaa E. Elshenawy, Mohammad Amjad Kamal

2020Current Pharmaceutical Design20 citationsDOI

Abstract

The latest SARS COV2 coronavirus contributes to a pandemic of millions of COVID-19. As there is no defensive immunity in humans and a virus can overcome inborn immune reaction, it can propagate unhindered, mostly in tissues contaminated. No unique therapies for COVID-19 contaminated patients are available at this time. The insights learned from previous respiratory viral infection control have given guidance into COVID- 19 therapy. Several complementary treatments have been tentatively introduced in hospital environments such as immune-modulators, antiviral, convalescent plasma transfusions and natural products. In COVID-19 patients, some of these therapies have provided substantial curative benefits. Moreover, numerous studies and clinical trials are being carried out in order to determine the efficacy of current pharmaceutical and natural products to establish possible therapeutic strategies for producing novel COVID-19 medicines. We summarized and defined the modes of mechanism, protection and efficacy on the existing therapeutic strategies for diseases linked to COVID-19 infection.

Topics & Concepts

Coronavirus disease 2019 (COVID-19)PandemicMedicineOutbreakSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Intensive care medicine2019-20 coronavirus outbreakClinical trialImmune systemCoronavirusVirusImmunologyVirologyDiseaseInfectious disease (medical specialty)Internal medicineCOVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 ResearchMedicinal Plants and Bioactive Compounds
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