Gold nanorod-assisted near-infrared light-mediated regulation of membrane ion channels activates apoptotic pathways
Juan Song, Jianbin Pan, Wei Zhao, Hong‐Yuan Chen, Jing‐Juan Xu
Abstract
We report a GNR-assisted NIR-activated tool that could open TRPV1 ion channels and regulate apoptotic protein expression, thereby inducing cell apoptosis, which might be an effective approach for cancer therapy.
Topics & Concepts
NanorodMembraneIon channelChemistryIonApoptosisNanotechnologyInfraredMaterials scienceBiophysicsBiochemistryBiologyReceptorOpticsPhysicsOrganic chemistryIon Channels and ReceptorsHydrogen's biological and therapeutic effectsCircadian rhythm and melatonin