Discovery of a novel, highly potent EZH2 PROTAC degrader for targeting non-canonical oncogenic functions of EZH2
Julia Velez, Brandon Dale, Kwang‐Su Park, H. Ümit Kanıskan, Xufen Yu, Jian Jin
Topics & Concepts
ChemistryEZH2Non canonicalComputational biologyStereochemistryBiochemistryCell biologyMethylationGeneBiologyProtein Degradation and InhibitorsHistone Deacetylase Inhibitors ResearchCancer-related gene regulation