A novel LC-MS/MS method for determination of the potential antiviral candidate favipiravir for the emergency treatment of SARS-CoV-2 virus in human plasma: Application to a bioequivalence study in Egyptian human volunteers
Mosaad I. Morsy, Eman G. Nouman, Youmna M. Abdallah, Mourd A. Zainelabdeen, Mohamed M Darwish, Ahmed Y. Hassan, Amira S. Gouda, Mamdouh R. Rezk, Ahmed M. Abdel‐Megied, Hoda M. Marzouk
Topics & Concepts
ChemistryChromatographyBioanalysisTriple quadrupole mass spectrometerProtein precipitationSelected reaction monitoringBioequivalenceElectrospray ionizationLiquid chromatography–mass spectrometryMass spectrometryTandem mass spectrometryPharmacokineticsMedicineInternal medicineSARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research StudiesSARS-CoV-2 detection and testing