Antioxidative role of palm grass rhizome ameliorates anxiety and depression in experimental rodents and computer-aided model
Md. Akramul Hoque, Shabbir Ahmad, Nishan Chakrabarty, Mohammad Forhad Khan, Mohammad Shah Hafez Kabir, Afrina Brishti, Md. Obayed Raihan, Aftab Alam, Md. Anwarul Haque, Shamima Nasrin, Md. Areeful Haque, A.S.M. Ali Reza
Abstract
for DPPH and reducing power capacity assay were found to be 18.56 and 193 μg/mL, respectively. Promising outcomes were noted for the determination of total phenolics, flavonoids, flavonols, and antioxidant capacity. In the case of computer-aided studies, nyasicoside showed promising binding energy for antidepressant and anxiolytic activities, whereas isocurculigine demonstrated promising effects as an antioxidant. Overall, these findings suggest that Me-RCR could be a favourable therapeutic candidate for the treatment of mental and psychiatric disorders, as well as a good source of antioxidants.