The cataract-linked RNA-binding protein Celf1 post-transcriptionally controls the spatiotemporal expression of the key homeodomain transcription factors Pax6 and Prox1 in lens development
Sandeep Aryal, Justine Viet, Bailey A. T. Weatherbee, Archana D. Siddam, Francisco Hernandez, Carole Gautier‐Courteille, Luc Paillard, Salil A. Lachke
Topics & Concepts
PAX6HomeoboxBiologyGene knockdownTranscription factorCell biologyEye developmentChromatin immunoprecipitationImmunoprecipitationRegulation of gene expressionRNAGene expressionMolecular biologyGeneGeneticsPromoterConnexins and lens biologyCancer-related molecular mechanisms researchMicroRNA in disease regulation