A sensitive electrochemical detection of metronidazole in synthetic serum and urine samples using low-cost screen-printed electrodes modified with reduced graphene oxide and C60
Elsa M. Materón, Ademar Wong, Tayane A. Freitas, Ronaldo C. Faria, Osvaldo N. Oliveira
Abstract
mol/L. This sensor was also capable of detecting MTZ in serum and urine, with recovery between 94% and 100%, which are similar to those of the standard chromatographic method (HPLC-UV). Because the C60-rGO-NF/SPE sensor is amenable to mass production and allows for MTZ determination with simple principles of detection, it fulfills the requirements of therapeutic drug monitoring programs.
Topics & Concepts
Detection limitChemistryGrapheneElectrochemical gas sensorAnalyteChromatographyElectrodeOxideElectrochemistryNanotechnologyMaterials scienceOrganic chemistryPhysical chemistryAdvanced biosensing and bioanalysis techniquesElectrochemical sensors and biosensorsElectrochemical Analysis and Applications