NKX2-1 controls lung cancer progression by inducing DUSP6 to dampen ERK activity
Kelley Ingram, Shiela C. Samson, Rediet Zewdu, Rebecca G. Zitnay, Eric L. Snyder, Michelle C. Mendoza
Topics & Concepts
MAPK/ERK pathwayDUSP6BiologyCancer researchGene silencingDownregulation and upregulationKinaseTumor progressionAdenocarcinomaLung cancerPhosphataseMetastasisCancerPhosphorylationCell biologyInternal medicineGeneGeneticsMedicineProtein phosphatase 2Protein Tyrosine PhosphatasesMelanoma and MAPK PathwaysCellular Mechanics and Interactions