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Enhancing the anti-tumor activity and reprogramming M2 macrophages by delivering siRNAs against SIRPα and STAT6 via M1 exosomes and combining with anti-PD-L1

Mahsa Taghavi-Farahabadi, Mohammad Mahmoudi, Nazanin Mojtabavi, Farshid Noorbakhsh, Hossein Ghanbarian, Ameneh Koochaki, Seyed Mahmoud Hashemi, Nima Rezaei

2024Life Sciences12 citationsDOI

Topics & Concepts

MicrovesiclesReprogrammingSmall interfering RNACancer researchChemistryRNA interferenceCell biologyBiologymicroRNATransfectionRNACellBiochemistryGeneImmune cells in cancerExtracellular vesicles in diseasePhagocytosis and Immune Regulation
Enhancing the anti-tumor activity and reprogramming M2 macrophages by delivering siRNAs against SIRPα and STAT6 via M1 exosomes and combining with anti-PD-L1 | Litcius