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A trispecific antibody targeting HER2 and T cells inhibits breast cancer growth via CD4 cells

Edward Seung, Zhen Xing, Lan Wu, Ercole Rao, Virna Cortez‐Retamozo, Beatriz Ospina, Liqing Chen, Christian Beil, Zhili Song, Bailin Zhang, Mikhail Levit, Gejing Deng, Andrew Hebert, Patrick Kirby, Aiqun Li, Emma-Jane Poulton, Rita Vicente, Audrey Garrigou, Peter Piepenhagen, Greg Ulinski, Michele Sanicola-Nadel, Dinesh S. Bangari, Huawei Qiu, Lily Pao, Dmitri Wiederschain, Ronnie R. Wei, Zhiyong Yang, Gary J. Nabel

2022Nature153 citationsDOI

Topics & Concepts

Cancer researchCytotoxic T cellT cellBiologyCD8Immune systemCD28ImmunologyCancerIn vitroBiochemistryGeneticsCAR-T cell therapy researchCancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses
A trispecific antibody targeting HER2 and T cells inhibits breast cancer growth via CD4 cells | Litcius