Synthetic regulatory genomics uncovers enhancer context dependence at the Sox2 locus
Ran Brosh, Camila Coelho, André M. Ribeiro-dos-Santos, Gwen Ellis, Megan S. Hogan, Hannah J. Ashe, Nicolette Somogyi, Raquel Ordóñez, Raven D. Luther, Emily Huang, Jef D. Boeke, Matthew T. Maurano
Topics & Concepts
BiologyEnhancerLocus (genetics)Computational biologyTranscription factorGenomicsGeneticsSOX2Context (archaeology)Genegenomic DNAFunctional genomicsGenomePaleontologyCRISPR and Genetic EngineeringGenomics and Chromatin DynamicsPluripotent Stem Cells Research