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In Vitro and Cellular Probes to Study PARP Enzyme Target Engagement

Tim J. Wigle, Danielle J. Blackwell, Laurie B. Schenkel, Yue Ren, W. David Church, Hetvi J. Desai, Kerren K. Swinger, Andrew G. Santospago, Christina R. Majer, Alvin Lu, Mario Niepel, Nicholas R. Perl, Melissa M. Vasbinder, Heike Keilhack, Kevin W. Kuntz

2020Cell chemical biology24 citationsDOIOpen Access PDF

Topics & Concepts

Poly ADP ribose polymeraseNAD+ kinaseEnzymeBiochemistryPolymerasePARP inhibitorIn vitroNicotinamide adenine dinucleotideIn vitro toxicologyChemistryRiboseNicotinamideBiologyMolecular biologyPARP inhibition in cancer therapyIntegrated Circuits and Semiconductor Failure AnalysisElectrostatic Discharge in Electronics
In Vitro and Cellular Probes to Study PARP Enzyme Target Engagement | Litcius