Organomercurial Lyase (MerB)-Mediated Demethylation Decreases Bacterial Methylmercury Resistance in the Absence of Mercuric Reductase (MerA)
Ian N Krout, Thomas Scrimale, Daria Vorojeikina, Eric S. Boyd, Matthew D. Rand
Abstract
Mercury is a globally distributed pollutant that poses a risk to wildlife and human health. The toxicity of mercury is influenced largely by microbially mediated biotransformation between its organic (methylmercury) and inorganic [Hg(II) and Hg 0 ] forms.
Topics & Concepts
DemethylationMethylmercuryChemistryBiochemistryReductaseLyaseBacteriaEscherichia coliEnzymeBiologyMicrobiologyGeneticsGeneOrganic chemistryDNA methylationGene expressionSeleniumMercury impact and mitigation studiesHeavy Metal Exposure and ToxicityMelamine detection and toxicity