The challenges to develop antibody-conjugated nanomedicine products
Liwei Hui, Wei Chen, Mohammad Najlah
Abstract
Nanomedicine becomes a key player especially as next generation medicine. Antibody-conjugated nanomedicine could significantly upgrade the treatment and expand application areas. However, there are extensive challenges of manufacturing those formulations as a final drug product. Here we provided the general technical guidance from the initial formulation construction including antibody conjugation to the downstream formulation development. We hope this technical note can help accelerate the translation of productizing the antibody-conjugated nanomedicines.
Topics & Concepts
NanomedicineConjugated systemProduct (mathematics)UpgradeNanotechnologyEngineeringMedicineComputer scienceChemistryMaterials scienceNanoparticleMathematicsGeometryOrganic chemistryOperating systemPolymerMonoclonal and Polyclonal Antibodies ResearchNanofabrication and Lithography TechniquesNanoparticle-Based Drug Delivery