Litcius/Paper detail

Botulinum neurotoxins exploit host digestive proteases to boost their oral toxicity via activating OrfXs/P47

Linfeng Gao, Maria B. Nowakowska, Katja Selby, Adina Przykopanski, Baohua Chen, Maren Krüger, François P. Douillard, Kwok Ho Lam, Peng Chen, Ting Huang, Nigel P. Minton, Martin B. Dorner, Brigitte G. Dorner, Andreas Rummel, Miia Lindström, Rongsheng Jin

2025Nature Structural & Molecular Biology17 citationsDOIOpen Access PDF

Topics & Concepts

ProteasesChemistryNeurotoxinToxicityHost (biology)ExploitBiochemistryBiologyEnzymeEcologyComputer scienceComputer securityOrganic chemistryBotulinum Toxin and Related Neurological DisordersHereditary Neurological DisordersNeurological disorders and treatments