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Neoadjuvant cabozantinib and nivolumab convert locally advanced hepatocellular carcinoma into resectable disease with enhanced antitumor immunity

Won Jin Ho, Qingfeng Zhu, Jennifer N. Durham, Aleksandra Popović, Stephanie Xavier, James M. Leatherman, Aditya Mohan, Guanglan Mo, Shu Zhang, Nicole Groß, Soren Charmsaz, Dongxia Lin, Derek Quong, Brad Wilt, Ihab R. Kamel, Matthew J. Weiss, Benjamin Philosophe, Richard A. Burkhart, William R. Burns, Chris Shubert, Aslam Ejaz, Jin He, Atul Deshpande, Ludmila Danilova, Genevieve Stein-O’Brien, Elizabeth A. Sugar, Daniel A. Laheru, Robert A. Anders, Elana J. Fertig, Elizabeth M. Jaffee, Mark Yarchoan

2021Nature Cancer346 citationsDOIOpen Access PDF

Topics & Concepts

CabozantinibNivolumabHepatocellular carcinomaMedicineOncologyInternal medicineImmunotherapyRenal cell carcinomaCancerHepatocellular Carcinoma Treatment and PrognosisCancer Immunotherapy and BiomarkersCancer Genomics and Diagnostics
Neoadjuvant cabozantinib and nivolumab convert locally advanced hepatocellular carcinoma into resectable disease with enhanced antitumor immunity | Litcius