Effective enantiomeric identification of aromatic amines by tyrosine-modified pillar[5]arenes as chiral NMR solvating agents
Luzhi Liu, Cuiguang Ma, Qin He, Yan Huang, Wengui Duan
Abstract
Two novel tyrosine-modified pillar[5]arenes have been synthesized and applied as chiral NMR solvating agents to establish an efficient <sup>1</sup>H NMR method for enantioselective recognition and configuration assignment towards α-aromatic ethylamines.
Topics & Concepts
ChemistryPillarEnantiomerEnantioselective synthesisCombinatorial chemistryCarbon-13 NMROrganic chemistryStereochemistryCatalysisEngineeringStructural engineeringMolecular spectroscopy and chiralityCrystallography and molecular interactionsAdvanced NMR Techniques and Applications