PRRSV infection activates NLRP3 inflammasome through inducing cytosolic mitochondrial DNA stress
Huawei Li, Xiaotian Yang, Yuzhen Song, Qingguo Zhu, Ziqian Liao, Yixuan Liang, Jianghao Guo, Bo Wan, Dengke Bao
Topics & Concepts
InflammasomeBiologyPorcine reproductive and respiratory syndrome virusAutophagyMitochondrial DNAMitochondrionMitochondrial ROSCytosolImmune systemInnate immune systemPathogenesisSignal transductionSecretionCell biologyImmunityVirologyImmunologyInflammationVirusGeneApoptosisGeneticsBiochemistryEnzymeAnimal Virus Infections Studiesinterferon and immune responsesVirus-based gene therapy research