Uveitis reactivation following recombinant zoster vaccination
Paige Richards, Maxwell Wingelaar, Karen R. Armbrust, Laura J. Kopplin
Abstract
PURPOSE: Describe three cases of uveitis reactivation following immunization with recombinant zoster vaccine (RZV). OBSERVATIONS: One patient developed reactivation of previously controlled multifocal choroiditis within one week of receiving RZV, requiring treatment with systemic corticosteroids. Two patients with previously controlled anterior uveitis developed new anterior segment inflammation after RZV; both were treated with topical corticosteroids and systemic antiviral therapy. CONCLUSION AND IMPORTANCE: Uveitis recurrence is an infrequent but serious potential ocular side effect of recombinant zoster vaccination.
Topics & Concepts
MedicineUveitisAnterior uveitisVaccinationImmunizationRecombinant DNASurgeryDermatologyImmunologyImmune systemChemistryBiochemistryGeneOcular Diseases and Behçet’s SyndromeHerpesvirus Infections and TreatmentsRetinal and Optic Conditions