The physio-affective phenome of major depression is strongly associated with biomarkers of astroglial and neuronal projection toxicity which in turn are associated with peripheral inflammation, insulin resistance and lowered calcium
Hussein Kadhem Al‐Hakeim, Tabarek Hadi Al-Naqeeb, Abbas F. Almulla, Michaël Maes
Topics & Concepts
Internal medicineInsulin resistanceEndocrinologyGlial fibrillary acidic proteinNeurotoxicityBiologyDiabetes mellitusMedicineToxicityImmunohistochemistryTryptophan and brain disordersStress Responses and CortisolTreatment of Major Depression