Atom- and step-economic 1,3-thiosulfonylation of activated allenes with thiosulfonates to access vinyl sulfones/sulfides
Xiao Xiao, Hongyu Tian, Yin-Qiu Huang, Yin‐Jie Lu, Jingjie Fang, Gao-Jie Zhou, Fen‐Er Chen
Abstract
A new type of organocatalyzed 1,3-difunctionalized thiosulfonylation has been developed to straightforwardly access highly functionalized vinyl sulfones. These products can also be transformed to vinyl sulfides via a base-promoted isomerization.
Topics & Concepts
IsomerizationAtom economyAtom (system on chip)ReagentChemistryCombinatorial chemistryOrganic chemistryComputer scienceCatalysisParallel computingSulfur-Based Synthesis TechniquesSynthesis and Catalytic ReactionsCatalytic C–H Functionalization Methods