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Spatial mapping reveals human adipocyte subpopulations with distinct sensitivities to insulin

Jesper Bäckdahl, Lovisa Franzén, Lucas Massier, Qian Li, Jutta Jalkanen, Hui Gao, Alma Andersson, Nayanika Bhalla, Anders Thorell, Mikael Rydén, Patrik L. Ståhl, Niklas Mejhert

2021Cell Metabolism30 citationsDOIOpen Access PDF

Abstract

Main text(Cell Metabolism 33, 1869–1882.e1–e6; September 7, 2021)In the original version of Figure 7G, the legend states that the image is from subject #2. However, the H&E image displayed in Figure 7G is from subject #5. This error has been corrected online. As this error occurred while writing the legend and not during data analysis, this error has no impact on the main results or conclusions of the publication. The authors apologize for this error and any confusion it may have caused. Main text(Cell Metabolism 33, 1869–1882.e1–e6; September 7, 2021)In the original version of Figure 7G, the legend states that the image is from subject #2. However, the H&E image displayed in Figure 7G is from subject #5. This error has been corrected online. As this error occurred while writing the legend and not during data analysis, this error has no impact on the main results or conclusions of the publication. The authors apologize for this error and any confusion it may have caused. (Cell Metabolism 33, 1869–1882.e1–e6; September 7, 2021) In the original version of Figure 7G, the legend states that the image is from subject #2. However, the H&E image displayed in Figure 7G is from subject #5. This error has been corrected online. As this error occurred while writing the legend and not during data analysis, this error has no impact on the main results or conclusions of the publication. The authors apologize for this error and any confusion it may have caused. Spatial mapping reveals human adipocyte subpopulations with distinct sensitivities to insulinBäckdahl et al.Cell MetabolismAugust 10, 2021In BriefTissue microarchitecture and cell composition are major determinants of organ function. Here, Bäckdahl et al. apply spatial transcriptomics to human white adipose tissue. This reveals that the tissue is more spatially defined than expected and identifies three distinct mature adipocyte subtypes with qualitatively different sensitivities to insulin stimulation in vivo. Full-Text PDF Open Access

Topics & Concepts

LegendSubject (documents)ConfusionComputer scienceImage (mathematics)Artificial intelligencePsychologyHistoryArt historyLibrary sciencePsychoanalysisAdipose Tissue and MetabolismAdipokines, Inflammation, and Metabolic Diseases
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