Activation of liver X receptors prevents emotional and cognitive dysfunction by suppressing microglial M1-polarization and restoring synaptic plasticity in the hippocampus of mice
Xinxin Xu, Xi Xiao, Yuxing Yan, Tao Zhang
Topics & Concepts
NeuroinflammationLiver X receptorNeuroscienceSynaptic plasticityDentate gyrusHippocampusAgonistPsychologyInternal medicineBiologyMedicineReceptorInflammationNuclear receptorBiochemistryGeneTranscription factorTryptophan and brain disordersNeuroinflammation and Neurodegeneration MechanismsStress Responses and Cortisol