A pH-responsive silica–metal–organic framework hybrid nanoparticle for the delivery of hydrophilic drugs, nucleic acids, and CRISPR-Cas9 genome-editing machineries
Yuyuan Wang, Pawan K. Shahi, Ruosen Xie, Huilong Zhang, Amr A. Abdeen, Nisakorn Yodsanit, Zhenqiang Ma, Krishanu Saha, Bikash R. Pattnaik, Shaoqin Gong
Topics & Concepts
Nucleic acidDrug deliveryChemistryGene deliveryCombinatorial chemistryDoxorubicin HydrochlorideGenome editingCas9NanotechnologyTransfectionCRISPRBiochemistryDoxorubicinMaterials scienceOrganic chemistryBiologyGeneGeneticsChemotherapyAdvanced biosensing and bioanalysis techniquesRNA Interference and Gene DeliveryCRISPR and Genetic Engineering