Enantioselective and collective total synthesis of pentacyclic 19-<i>nor</i>-clerodanes
Zhi‐Mao Zhang, Junliang Zhang, Quan Cai
Abstract
The concise and collective total synthesis of seven pentacyclic 19- nor -clerodane diterpenoids were achieved by a catalytic asymmetric inverse-electron-demand Diels–Alder (IEDDA) reaction and late-stage oxidative transformations.
Topics & Concepts
Enantioselective synthesisTotal synthesisStereochemistryChemistryOrganic chemistryCatalysisChemical synthesis and alkaloidsMarine Sponges and Natural ProductsSynthetic Organic Chemistry Methods