SIAH1 promotes senescence and apoptosis of nucleus pulposus cells to exacerbate disc degeneration through ubiquitinating XIAP
Shibing Fang, Fang-jun Zeng, Rongchun Chen, Mingheng Li
Topics & Concepts
SenescenceXIAPApoptosisCell biologyBiologyGene knockdownMolecular biologyUbiquitinInflammationDownregulation and upregulationCancer researchImmunologyProgrammed cell deathBiochemistryCaspaseGeneSpine and Intervertebral Disc PathologySpinal Hematomas and ComplicationsOrthopaedic implants and arthroplasty