Oxidative stress abrogates the degradation of KMT2D to promote degeneration in nucleus pulposus

Wenbin Xu, Xuyang Zhang, Gang Liu, Mingjie Zhu, Yizheng Wu, Zhiwei Jie, Ziang Xie, Shiyu Wang, Qingliang Ma, Shunwu Fan, Xiangqian Fang

2020Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease26 citationsDOI

Topics & Concepts

Oxidative stressDegeneration (medical)MMP3Gene knockdownCell biologyChemistryMatrix metalloproteinaseReactive oxygen speciesBiologyBiochemistryGene expressionApoptosisGeneMedicinePathologySpine and Intervertebral Disc PathologyMusculoskeletal pain and rehabilitationSpinal Cord Injury Research