A novel electrospun nanofiber system with PEGylated paclitaxel nanocrystals enhancing the transmucus permeability and in situ retention for an efficient cervicovaginal cancer therapy
Huan Duan, Haini Chen, Chenrui Qi, Feng-mei Lv, Jun Wang, Yicheng Liu, Zhepeng Liu, Yu Liu
Topics & Concepts
PaclitaxelNanofiberPermeability (electromagnetism)In situPharmacologyCancer therapyChemistryMedicineCancerMaterials scienceNanotechnologyInternal medicineOrganic chemistryBiochemistryMembraneAdvanced Drug Delivery SystemsElectrospun Nanofibers in Biomedical ApplicationsProteoglycans and glycosaminoglycans research