Pre-encoded responsiveness to type I interferon in the peripheral immune system defines outcome of PD1 blockade therapy
Giselle M. Boukhaled, Ramy Gadalla, Heidi Elsaesser, Diala Abd-Rabbo, Rene Quevedo, S.Y. Cindy Yang, Mengdi Guo, Ben X. Wang, Babak Noamani, Diana Gray, Sally C. M. Lau, Kirsty Taylor, Kyaw Aung, Anna Spreafico, Aaron R. Hansen, Samuel D. Saibil, Naoto Hirano, Cynthia J. Guidos, Trevor J. Pugh, Tracy L. McGaha, Pamela S. Ohashi, Adrian G. Sacher, Marcus O. Butler, David G. Brooks
Topics & Concepts
BlockadePeripheralImmune systemImmunologyMedicineInterferonImmune checkpointOutcome (game theory)ImmunotherapyReceptorInternal medicineMathematicsMathematical economicsImmune Cell Function and InteractionT-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers