Phorbol Diesters and 12-Deoxy-16-hydroxyphorbol 13,16-Diesters Induce TGFα Release and Adult Mouse Neurogenesis
Abdellah Ezzanad, Ricardo Gómez‐Oliva, Felipe Escobar-Montaño, Mónica Díez-Salguero, Noelia Geribaldi‐Doldán, Samuel Domínguez‐García, José Manuel Botubol‐Ares, Carolina de los Reyes, Rosa Durán‐Patrón, Pedro Nunez‐Abades, Antonio J. Macías‐Sánchez, Carmen Castro, Rosario Hernández‐Galán
Abstract
when administered intranasally to mice.
Topics & Concepts
NeurogenesisChemistryProgenitor cellCell growthIn vivoNeural stem cellTransforming growth factorPhorbolLipophilicityIn vitroCellCell biologyBiochemistryStereochemistryStem cellSignal transductionBiologyBiotechnologyProtein kinase CBioactive Natural Diterpenoids ResearchPhytochemistry and Bioactive CompoundsBiological and pharmacological studies of plants