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Diagonal integration of multimodal single-cell data: potential pitfalls and paths forward

Yang Xu, Rachel Patton McCord

2022Nature Communications37 citationsDOIOpen Access PDF

Abstract

Diagonal integration of multimodal single-cell data emerges as a trending topic. However, empowering diagonal methods for novel biological discoveries requires bridging huge gaps. Here, we comment on potential risks and future directions of diagonal integration for multimodal single-cell data.

Topics & Concepts

DiagonalBridging (networking)Computer scienceData integrationData miningMathematicsGeometryComputer networkSingle-cell and spatial transcriptomicsGene Regulatory Network AnalysisAdvanced Biosensing Techniques and Applications